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For Novel B7-H4 Antibody FPA150
January 4, 2018
By: Betsy Louda
Five Prime Therapeutics has submitted an Investigational New Drug (IND) application for FPA150, a first-in-class immuno-oncology antibody that targets B7-H4. FPA150 was discovered using the company’s protein therapeutics platform and anticipates initiating a Phase 1 trial of FPA150 during the first half of 2018. FPA150 is a high affinity, afucosylated monoclonal antibody designed with a dual mechanism of action: blocking a T cell checkpoint pathway and delivering enhanced an...
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